Proofpoint Inc., a leading cybersecurity and compliance company, has announced an expanded global partnership with Microsoft, leveraging Microsoft Azure to drive AI-powered threat protection and data security. By hosting future innovations on Azure, Proofpoint aims to enhance human-centric security capabilities, providing organizations with stronger defenses against evolving cyber threats.
“Built on Microsoft Azure, we’re delivering advanced, preventive protection for the most important layer in cybersecurity—the human layer.”
— Darren Lee, EVP & GM, Threat Protection Group at Proofpoint
Highlights of the Partnership
Enhanced Human-Centric Security – Focuses on securing the human layer, where 90% of breaches originate
Seamless API-Driven Integration – Strengthens Microsoft 365 security with advanced email & data protection
AI-Powered Threat Intelligence – Faster threat detection, automated response workflows, and proactive risk mitigation
Innovating with Microsoft Azure
Proofpoint will migrate its human-centric platform and services—including Nexus intelligence technologies—to Azure by Q2 2025. The integration will deliver:
Advanced Email Security – Protection against phishing, ransomware, and business email compromise (BEC)
Enhanced Data Protection – Strengthens Microsoft 365 security posture
Lower Operational Costs – Improves efficiency with automation and reduced complexity
Protection Against GenAI Risks – Addresses emerging threats from AI-powered tools
Integrating Proofpoint’s Threat Intelligence with Microsoft Sentinel
A key element of this collaboration is the integration of Proofpoint’s Nexus threat intelligence into Microsoft Sentinel via Proofpoint Targeted Attack Protection (TAP) SIEM APIs. This will provide security teams with:
Richer Insights & Faster Incident Response
Proactive Threat Defense with Automated Workflows
Stronger Detection & XDR Capabilities
Availability & Next Steps
Q2 2025 – New integrations and AI-driven innovations to be launched
Available Today – Proofpoint API, Adaptive Email DLP with Microsoft Purview, and TAP with Microsoft Defender for Endpoint
This partnership marks a significant step forward in cybersecurity, enabling enterprises to detect, prevent, and respond to cyber threats with greater speed and accuracy.
